Benefits of Nitric Oxide

Nitric oxide (NO) is a colorless gas that is naturally produced in the body. It acts as a signaling molecule and plays a crucial role in various physiological processes. Nitric oxide is produced by the enzyme nitric oxide synthase (NOS) from the amino acid L-arginine. Research has shown that there are other things that cause a nitric oxide response and this is becoming more and more studied due to new research. One important thing it does: It functions as a vasodilator. This helps regulate blood pressure and improve circulation. Nitric oxide also plays a role in the immune system, neurotransmission, and cell communication. Additionally, it is involved in the regulation of inflammation and the relaxation of smooth muscles.

Nitric oxide (NO) has several important functions in the body:

Vasodilation: Nitric oxide acts as a potent vasodilator, relaxing and widening blood vessels. This helps to improve blood flow and regulate blood pressure. Proper blood flow is essential for delivering oxygen and nutrients to various tissues and organs in the body. For this reason many people use this in a prework out supplement.

Neurotransmission: Nitric oxide acts as a neurotransmitter in the central nervous system, facilitating communication between nerve cells. It plays a role in memory, learning, and cognitive functions.

Immune system regulation: Nitric oxide is involved in the immune response, helping to regulate inflammation and defend against pathogens. It can act as a signaling molecule for immune cells, promoting their activation and function.

Cell communication: Nitric oxide is involved in cell signaling and communication. It can influence various cellular processes, including gene expression, protein synthesis, and cell growth.

What happens when someone has low Nitric oxide levels?

When the levels of nitric oxide (NO) in the body are low, it can have several effects on various physiological processes. Some potential consequences of low nitric oxide levels include:

Impaired blood flow: Nitric oxide is a potent vasodilator, meaning it relaxes and widens blood vessels. When nitric oxide levels are low, blood vessels may constrict, leading to reduced blood flow. This can result in poor circulation, increased blood pressure, and decreased oxygen and nutrient delivery to tissues and organs.

Cardiovascular issues: Low nitric oxide levels can contribute to cardiovascular problems such as hypertension (high blood pressure), atherosclerosis (hardening of the arteries), and endothelial dysfunction (impaired function of the inner lining of blood vessels). These conditions can increase the risk of heart disease, heart attacks, and strokes.

Reduced immune function: Nitric oxide plays a role in regulating the immune response. Low levels of nitric oxide may impair immune function, making individuals more susceptible to infections and inflammatory conditions.

Cognitive impairment: Nitric oxide is involved in neurotransmission and cognitive functions. Low levels of nitric oxide may affect memory, learning, and cognitive performance.

Erectile dysfunction: Nitric oxide is crucial for the relaxation of smooth muscles in the penis, allowing for increased blood flow and the achievement of an erection. Low nitric oxide levels can contribute to erectile dysfunction.

It is important to note that low nitric oxide levels can be caused by various factors, including aging, certain medical conditions, poor diet, lack of exercise, and smoking. If you suspect low nitric oxide levels, it is advisable to consult a healthcare professional for proper evaluation and guidance. If you are low there are supplements that help to increase nitric oxide in the body helping to improve the areas that may be struggling due to having low levels.

Nitric oxide and training:

Nitric oxide (NO) supplements are often marketed as muscle-building aids due to their potential effects on blood flow and nutrient delivery to muscles. Here’s how nitric oxide supplements may help in muscle building:

Increased blood flow: Because Nitric oxide is a potent vasodilator, and is increasing blood flow to muscles, nitric oxide supplements may enhance the delivery of oxygen, nutrients, and anabolic compounds (such as amino acids) to the muscles. This increased blood flow can potentially improve muscle performance and recovery.

Enhanced nutrient uptake: Improved blood flow facilitated by NO supplements may enhance the uptake of nutrients, such as amino acids and glucose, by muscle cells. This can support muscle growth, repair, and recovery.

Increased muscle pump: Nitric oxide supplements are often associated with the “pump” sensation during workouts. This refers to the temporary swelling and engorgement of muscles due to increased blood flow. While the pump itself does not directly contribute to muscle growth, it can provide a psychological boost and motivation during workouts.

Improved endurance and performance: By increasing blood flow and oxygen delivery, NO supplements may help improve endurance and exercise performance. This can potentially lead to more intense and productive workouts, which can contribute to muscle growth over time.

It’s important to note that the effectiveness of nitric oxide supplements in muscle building can vary among individuals, and the scientific evidence supporting their benefits is mixed. Additionally, a balanced diet, proper training, and adequate rest are crucial factors in muscle building. Consulting with a healthcare professional or a registered dietitian before starting any supplement regimen is recommended to ensure it aligns with your specific goals and health status.

Overall, nitric oxide is essential for maintaining proper cardiovascular function, regulating the immune system, and facilitating communication between cells. Its role in vasodilation and blood flow regulation is particularly important for overall health and well-being

Michelle LeSueur BeP, CNC, CSN, CNS, CPT

Why Vitamin C Should be Taken Daily

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that is essential for the proper functioning of the body. It is not produced naturally by the human body, so it must be obtained through diet or supplements.

Here are some key facts about vitamin C:

Functions: Vitamin C has numerous important functions in the body. It is a powerful antioxidant that helps protect cells from damage caused by free radicals. It is also involved in collagen synthesis, which is essential for the health and maintenance of connective tissues, skin, blood vessels, and bones. Additionally, vitamin C plays a role in the absorption of iron, supports the immune system, and helps in the synthesis of certain neurotransmitters.

Immune system support: Vitamin C is well-known for its immune-boosting properties. It helps stimulate the production of white blood cells, which are crucial for fighting off infections and diseases. It also enhances the function of these immune cells, helping the body defend against pathogens.

Antioxidant properties: As an antioxidant, vitamin C helps neutralize harmful free radicals in the body. Free radicals are unstable molecules that can cause oxidative stress, leading to cell damage and various health issues. By neutralizing these free radicals, vitamin C helps protect against chronic diseases and supports overall health.

Collagen synthesis: Vitamin C is essential for the synthesis of collagen, a protein that provides structure and strength to various tissues in the body. Collagen is important for healthy skin, bones, blood vessels, and tendons. Vitamin C deficiency can lead to weakened collagen production, resulting in issues like scurvy, poor wound healing, and joint problems. It helps promote wound healing and keeps the skin healthy and youthful.

Iron absorption: Vitamin C enhances the absorption of iron from plant-based sources, such as spinach and lentils. It converts non-heme iron into a form that is easier for the body to absorb, preventing iron deficiency anemia. The bioflavonoids in it help with the absorption of iron so taking this along with your iron will help you utilize it better.

Reduced risk of chronic diseases: Adequate intake of vitamin C has been associated with a lower risk of chronic diseases, including heart disease, high blood pressure, certain cancers, and age-related macular degeneration.

Helps reduce Uric Acid: There are many people who struggle with high uric acid. When your levels are high it causes some people to have gout. Anyone that has had gout can testify that this is a very painful inflammatory issue. Several studies have shown that vitamin C may help reduce uric acid in the blood and protect against gout attacks.

Common cold prevention: While vitamin C may not prevent the common cold, it has been shown to reduce the duration and severity of cold symptoms. Regular intake of vitamin C may help support the immune system and alleviate symptoms faster.

So what are some of the signs of deficiency?

  • Rough, Bumpy Skin
  • Corkscrew-Shaped Body Hair
  • Bright Red Hair Follicles
  • Spoon-Shaped Fingernails With Red Spots or Lines
  • Dry, Damaged Skin
  • Easy Bruising
  • Slowly Healing Wounds
  • Painful, Swollen Joints
  • Weak bones
  • Bleeding gums
  • Poor immunity
  • Persistent Anemia
  • Fatigue
  • Chronic inflammation

Dietary recommendations: The recommended daily intake of vitamin C varies depending on age, sex, and life stage. For adults, the recommended dietary allowance (RDA) is around 75-90 milligrams per day for women and 90-120 milligrams per day for men. However, certain conditions or situations, such as pregnancy, breastfeeding, smoking, or illness, may require higher vitamin C intake. I would also add people that have a poor diet. If you eat out a lot and are not eating fruits and vegetables then supplementing is a must.

Some of the best sources of Vitamin C are found in various fruits and vegetables, including citrus fruits (such as oranges and lemons), strawberries, kiwi, bell peppers, broccoli, and spinach. It can also be obtained through dietary supplements.

Taking vitamin C in a liposomal or nano form is best because if you take it in an oral form, for many it will cause them to have loose bowels. Many times people need a high dose of it and so it is difficult for them to get what they really need because their gut and intestines just can’t handle it. Because a nano form bypasses the gut it also increases the absorption of the vitamin C so you can take less and have better results.

If you have ever thought about doing your own line, this is a great supplement to start with. If you’re looking for high-quality and customized supplement manufacturing, consider Nano9, your trusted partner for all your supplement needs.

Michelle LeSueur BeP, CNC, CSN, CNS, CPT

Gymnema Sylvestre and Its Role in Blood Sugar and Weight Management

Each year the number of cases of blood sugar related diseases seem to climb. We now have more morbidly overweight people than overweight people today because of poor choices in diet. Many people eat out daily compared to 20 years ago. These foods have hidden sugars and other harmful chemicals that move people towards obesity. I recently saw a picture of people at the beach from the late 70’s early 80’s and almost no one was fat or had any form of weight issues. Today it is quite the opposite. It was unheard of during that time or even 30 years ago to see obese or morbidly obese children. If parents really understood the health ramifications tied to that they would definitely make changes to the foods in their home. There are many natural things today to help support healthy blood sugar levels and help with sugar cravings. One of these ingredients is Gymnema Sylvestre.

Gymnema Sylvestre, also known as Gymnema or Gurmar, is a woody climbing shrub native to India, Africa, and Australia. It has been used in traditional Ayurvedic medicine for centuries. Here are some potential benefits associated with Gymnema Sylvestre:

Blood sugar control: Gymnema Sylvestre is most commonly known for its potential to help regulate blood sugar levels. It contains compounds called gymnemic acids that may help reduce sugar cravings, inhibit the absorption of sugar in the intestines, and enhance insulin production.

It is often used as a natural remedy for managing diabetes and supporting healthy blood sugar levels.

Weight management: Gymnema Sylvestre may also have potential benefits for weight management. By reducing sugar cravings and inhibiting sugar absorption, it may help control appetite and prevent overeating. Additionally, it may support healthy metabolism and energy utilization.

Cholesterol management: Some studies suggest that Gymnema Sylvestre may help lower cholesterol levels. It may inhibit the absorption of dietary fats and cholesterol in the intestines, potentially reducing overall cholesterol levels and promoting heart health.

Anti-inflammatory properties: Gymnema Sylvestre has been found to possess anti-inflammatory properties. It may help reduce inflammation in the body, which is associated with various chronic diseases and conditions.

Antioxidant activity: Gymnema Sylvestre contains antioxidants that help protect cells from damage caused by free radicals. These antioxidants may have a positive impact on overall health and well-being.

Digestive health: In traditional medicine, Gymnema Sylvestre has been used to support digestive health. It may help improve digestion, reduce gastric acid secretion, and alleviate gastrointestinal discomfort.

There are several reasons why someone might consider using Gymnema Sylvestre:

Blood sugar management: Gymnema Sylvestre has been traditionally used for its potential to help regulate blood sugar levels. If you have diabetes or struggle with blood sugar control, Gymnema Sylvestre may be worth considering as a natural supplement to support healthy blood sugar levels.

Sugar cravings: Gymnema Sylvestre has been reported to help reduce sugar cravings. If you find yourself constantly craving sugary foods and beverages, Gymnema Sylvestre may help curb those cravings and support healthier eating habits.

Weight management: By reducing sugar cravings and potentially aiding in weight management, Gymnema Sylvestre may be beneficial for those looking to lose weight or maintain a healthy weight.

Cholesterol control: Gymnema Sylvestre has shown potential in lowering cholesterol levels. If you have high cholesterol or are concerned about your heart health, Gymnema Sylvestre may be worth exploring as a natural supplement to support cholesterol management.

Anti-inflammatory support: Gymnema Sylvestre possesses anti-inflammatory properties, which may be beneficial for individuals dealing with chronic inflammation or inflammatory conditions.

Digestive health: Gymnema Sylvestre has been used traditionally to support digestive health. If you experience digestive issues or discomfort, Gymnema Sylvestre may help improve digestion and alleviate symptoms.

It’s important to note that while Gymnema Sylveste shows promise in various areas, more research is needed to fully understand its effects and potential benefits. Individual results may vary. As with any herbal supplement, it is advisable to consult with a healthcare professional and/or pharmacist before starting Gymnema Sylvestre or any new supplement regimen, especially if you have any underlying health conditions or are taking medications. They can provide personalized advice based on your specific needs and circumstances.

If you have ever thought about doing your own line or you currently have a line, you may want to create a product containing Gymnema Sylvestre such as a blood sugar or weight loss product. If you’re looking for high-quality and customized supplement manufacturing, consider Nano9, your trusted partner for all your supplement needs.

Michelle LeSueur BeP, CNC, CSN, CNS, CPT

Why are Omega-3 fatty acids so important to our health?

Omega-3 fatty acids are the second in the top 3 supplements purchased today.  Omega 3,, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are essential fats that play a crucial role in brain health, heart health, and inflammation regulation. They are commonly consumed through fish oil supplements or derived from plant-based sources like algae.

Omega 3 fatty acids are important for several reasons:

Heart Health: Omega-3 fatty acids, particularly EPA and DHA, have been extensively studied for their cardiovascular benefits. They can help reduce triglyceride levels, lower blood pressure, decrease inflammation, and improve overall heart health. Consuming omega-3 fatty acids through diet or supplements has been associated with a reduced risk of heart disease and related complications.

Brain Function and Mental Health: Omega-3 fatty acids are crucial for brain development and function. DHA, in particular, is a major structural component of the brain and plays a role in maintaining cognitive function and supporting memory and learning. Adequate omega-3 intake has been linked to a reduced risk of cognitive decline, improved mood, and a lower incidence of mental health disorders such as depression and anxiety.

Inflammation and Immune Response: Omega-3 fatty acids possess anti-inflammatory properties. They help regulate the body’s inflammatory response, which is important for maintaining a balanced immune system. Chronic inflammation is associated with various health conditions, including cardiovascular disease, arthritis, and certain cancers. Omega-3 fatty acids can help reduce inflammation and promote a healthier immune response.

Eye Health: DHA, one of the omega-3 fatty acids, is also found in high concentrations in the retina of the eye. Adequate intake of omega-3 fatty acids has been associated with a reduced risk of age-related macular degeneration (AMD) and dry eye syndrome, helping to maintain good eye health and vision.

Pregnancy and Early Development: Omega-3 fatty acids are crucial during pregnancy and early childhood development. They play a vital role in the development of the baby’s brain and eyes. Pregnant women are often advised to consume sufficient omega-3 fatty acids to support the baby’s growth and development.

EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are two types of omega-3 fatty acids that are commonly found in fatty fish and certain algae. They are considered long-chain omega-3 fatty acids and are known for their health benefits.

EPA is an omega-3 fatty acid that is primarily associated with anti-inflammatory effects. It plays a crucial role in reducing inflammation in the body, particularly in relation to cardiovascular health. EPA has been shown to help lower triglyceride levels, reduce blood clotting, and decrease inflammation in blood vessels, thereby supporting heart health.  DHA is another omega-3 fatty acid that is essential for brain health and development. It is a major structural component of the brain and is important for maintaining cognitive function, memory, and overall brain health. DHA is also found in high concentrations in the retina of the eye, contributing to good vision and eye health.

Both EPA and DHA are considered essential fatty acids, meaning that our bodies cannot produce them in sufficient quantities and they must be obtained through dietary sources or supplements. Fatty fish, such as salmon, mackerel, and sardines, are rich sources of EPA and DHA. Additionally, certain types of algae-based supplements are available for individuals following a vegetarian or vegan diet who want to ensure an adequate intake of these omega-3 fatty acids.

Deficiencies in EPA and DHA, can manifest in various signs and symptoms. Here are some potential indicators of low EPA and DHA levels:

Cognitive and Mental Health Issues: Omega-3 fatty acids, particularly DHA, are crucial for brain health and cognitive function. A deficiency in EPA and DHA may contribute to cognitive decline, memory problems, difficulty concentrating, and impaired learning abilities. It has also been associated with an increased risk of mental health disorders such as depression, anxiety, and mood swings.

Dry Skin and Hair: EPA and DHA play a role in maintaining healthy skin and hair. A deficiency in these omega-3 fatty acids may lead to dry, flaky skin, rough patches, and brittle hair.

Joint Pain and Inflammation: EPA, in particular, has anti-inflammatory properties and helps regulate the body’s inflammatory response. A deficiency in EPA and DHA may contribute to increased joint pain, stiffness, and inflammation, potentially exacerbating conditions like arthritis.

Fatigue and Mood Swings: Omega-3 fatty acids are involved in energy production and mood regulation. Low levels of EPA and DHA may result in fatigue, low energy levels, and mood swings.

Vision Problems: DHA is highly concentrated in the retina of the eye and is essential for maintaining good vision. Inadequate levels of DHA may contribute to vision problems, including dry eyes, poor night vision, and an increased risk of age-related macular degeneration (AMD).

It’s important to note that these signs and symptoms can be caused by various factors, and a deficiency in EPA and DHA may not be the sole cause. If you suspect a deficiency, it is advisable to consult with a healthcare professional who can assess your specific situation and recommend appropriate measures, such as dietary changes or supplementation.

If you are looking to increase your omega-3 fatty acids, you can be obtained through dietary sources like fatty fish (such as salmon, mackerel, and sardines), flaxseeds, and walnuts, supplementation is often recommended to ensure adequate intake, especially for individuals who do not consume enough of these foods.

Michelle LeSueur BeP, CNC, CSN, CNS, CPT

The importance of Sleep

Did you know that 63% of Americans struggle with sleep issues? 

60% of Americans rarely feel rested and energized. 

42 % of Americans start feeling tired as early as noon, according to new research.

(46%) reported that they regularly have trouble falling asleep:

Why sleep is so important: 

  • Muscle repair
  • Your brain recharges and Helps brain function
  • Protein synthesis
  • Tissue growth
  • Hormone release
  • Keeps weight under control.
  • Reduces disease risk.
  • Keeps emotions in check.
  • Your cells repair themselves
  • Your body releases important hormones
  • You eat more, have higher levels of GHRELIN, and less feeling of fullness compared to those that got good sleep. They eat and crave higher caloric food

The problem of people not getting enough sleep is quite significant in today’s society. Sleep deprivation has become increasingly prevalent due to various factors such as demanding work schedules, excessive use of electronic devices, stress, and lifestyle choices. According to the Centers for Disease Control and Prevention (CDC), about one-third of adults in the United States do not get the recommended 7-9 hours of sleep per night.

Lack of sleep can have numerous negative effects on individuals’ physical and mental health. It can lead to decreased cognitive function, impaired memory, reduced productivity, increased risk of accidents, weakened immune system, weight gain, and heightened risk of chronic conditions like diabetes, cardiovascular diseases, and mental health disorders. Furthermore, insufficient sleep has broader societal implications. It can impact workplace productivity, increase healthcare costs, and contribute to accidents and errors in various fields, including transportation and healthcare.

Addressing the issue of inadequate sleep requires awareness, education, and changes in both individual behaviors and societal norms. Encouraging healthy sleep habits, promoting work-life balance, implementing flexible work schedules, and reducing the use of electronic devices before bedtime are some potential strategies to mitigate this problem.

Sleep and your weight

Weightloss happens when we sleep!! Not getting enough sleep can have a significant impact on weight and contribute to weight gain or difficulty in losing weight. Here are a few ways in which lack of sleep can affect weight:

Increased appetite

Sleep deprivation can disrupt the balance of hormones that regulate hunger and satiety, such as ghrelin and leptin. Ghrelin, the hormone that stimulates appetite, tends to increase, while leptin, the hormone that signals fullness, decreases when you don’t get enough sleep. This hormonal imbalance can lead to increased cravings, overeating, and a higher calorie intake.

Impaired metabolism

Lack of sleep can negatively affect your metabolism, specifically by impairing insulin sensitivity. Insulin is responsible for regulating blood sugar levels, and when your body becomes less sensitive to insulin, it can lead to higher blood sugar levels and an increased risk of developing insulin resistance and type 2 diabetes. Insulin resistance can also promote fat storage, particularly around the abdominal area.

Changes in food choices

Sleep deprivation can influence food choices, making individuals more likely to opt for high-calorie, sugary, and fatty foods. This can be attributed to the impact of sleep deprivation on the brain’s reward centers, leading to a greater desire for unhealthy foods.

Reduced physical activity

When you’re sleep-deprived, you may feel fatigued and lack the energy or motivation to engage in physical activity. This can lead to a sedentary lifestyle and a decrease in calorie expenditure, contributing to weight gain.

It’s important to note that while lack of sleep can influence weight gain, it is just one factor among many that contribute to overall weight management. A balanced diet, regular exercise, and other lifestyle factors also play crucial roles in maintaining a healthy weight.

Not getting enough sleep can have a significant impact on brain function and memory. Here are a few ways in which sleep deprivation affects the brain:

Cognitive function

Sleep is essential for optimal cognitive function, including attention, concentration, problem-solving, and decision-making. Lack of sleep can impair these cognitive processes, leading to decreased productivity, difficulty in learning new information, and reduced overall mental performance.

Memory consolidation

During sleep, the brain consolidates and strengthens memories, transferring information from short-term memory to long-term memory. Insufficient sleep can disrupt this process, making it more challenging to retain and recall information. It can affect both declarative memory (facts, events) and procedural memory (skills, habits).

Learning ability 

Sleep deprivation can hinder the brain’s ability to acquire new knowledge and skills. It impairs the brain’s ability to form new neural connections and integrate information, making it harder to learn and retain new information effectively.

Emotional regulation

Sleep deprivation can impact emotional regulation and increase emotional reactivity. It can lead to mood swings, irritability, and difficulty managing stress and emotions. Lack of sleep can also contribute to an increased risk of developing mental health disorders such as anxiety and depression.

Brain structure and health

Chronic sleep deprivation has been associated with structural changes in the brain, including reduced gray matter volume and alterations in connectivity between brain regions. It can also increase the risk of neurodegenerative diseases, such as Alzheimer’s disease.

It’s important to prioritize adequate sleep to support optimal brain function, memory consolidation, and overall cognitive health. Getting the recommended 7-9 hours of sleep per night can help improve cognitive performance, memory retention, and emotional well-being.

Building Your Brand Through White Label Manufacturing: A Strategic Approach

In today’s competitive market, building a strong brand presence is crucial for business success. White label manufacturing offers a strategic avenue for entrepreneurs and businesses to establish and grow their brand. This article explores the concept of white label manufacturing and provides insights into how it can be leveraged to build a successful brand.

1.Understanding White Label Manufacturing:

White label manufacturing involves partnering with a manufacturer who produces goods or products that are then rebranded and sold under a different brand name. This allows businesses to focus on marketing, sales, and brand development while relying on the expertise and capabilities of the manufacturing partner.

2. Choosing the Right Manufacturing Partner:

Selecting the right white label manufacturing partner is essential for brand building. Consider factors such as the manufacturer’s reputation, quality control processes, production capacity, and ability to meet your specific requirements. A reliable partner will ensure that your brand maintains consistent quality and meets customer expectations.

3. Customizing and Differentiating Your Product:

While white label manufacturing involves using pre-existing products, it is crucial to customize and differentiate them to align with your brand identity. This can be achieved through unique packaging, branding, product features, or additional value-added services. By adding your brand’s touch, you create a distinct identity that sets you apart from competitors.

4. Quality Assurance and Brand Reputation:

Maintaining high-quality standards is vital for building a reputable brand. Work closely with your manufacturing partner to establish quality control measures and ensure that the products meet or exceed industry standards. Consistently delivering quality products will enhance your brand’s reputation and foster customer loyalty.

5. Effective Branding and Marketing Strategies:

White label manufacturing provides an opportunity to focus on branding and marketing efforts. Develop a comprehensive brand strategy that aligns with your target market and brand values. Invest in professional branding elements such as logos, packaging, and website design to create a cohesive and visually appealing brand identity. Implement effective marketing strategies, including digital marketing, social media campaigns, influencer collaborations, and content creation, to increase brand visibility and reach your target audience.

6. Building Customer Trust and Loyalty:
Transparency and open communication are key to building trust with your customers. Clearly communicate that your products are white label and emphasize the quality and value they offer. Provide exceptional customer service, promptly address customer concerns, and actively seek feedback to continuously improve your products and brand experience. Building trust and fostering customer loyalty will contribute to long-term brand success.

White label manufacturing presents a valuable opportunity for entrepreneurs and businesses to build their brand effectively. By partnering with a reliable manufacturing partner, customizing products, maintaining quality standards, and implementing strong branding and marketing strategies, businesses can establish a reputable brand presence in the market. Embrace the potential of white label manufacturing as a strategic approach to brand building and unlock new avenues for growth and success.

How to Choose the Right Manufacture for You

Many people take supplements today.  In fact, a survey done in 2017 showed that 76% of people do.  There are many companies that do manufacturing and it may be difficult to know what to choose when looking for a supplement manufacturer.

What are things to look for when looking for quality supplement manufacturing?

When looking for quality supplement manufacturing, there are several important factors to consider. Here are some key things to look for:

1. Good Manufacturing Practices (GMP) certification: Ensure that the manufacturer has a up to date GMP, which are industry standards for quality control and safety in the production of dietary supplements.

Nano 9 is a Good Manufacturing Practices (GMP) certified company.  We follow all the guidelines and safety to ensure a great product. 

2. Quality control measures: Look for manufacturers that have robust quality control systems in place, including testing raw materials for purity and potency, conducting in-process testing during manufacturing, and performing finished product testing.

Quality is very important to Nano9 and we use this throughout our process and when each product is completed we send it out for independent testing to validate.

3. Ingredient sourcing: Check if the manufacturer sources high-quality ingredients from reputable suppliers. They should have a system in place to verify the authenticity and purity of the ingredients used in their supplements.

When sourcing raw ingredients you can buy a variety of ingredients in various grades.  Nano9 always chooses the highest quality ingredients when putting any product together.

4. Research and development capabilities: Consider manufacturers that invest in research and development to stay updated with the latest scientific advancements. This ensures that their products are formulated based on scientific evidence and are effective.

Because we are a nanotechnology company it is imperative that we stay up to date with things.  Our biochemist and in house practitioner are always in classes to stay up with what is going on in the supplement industry to ensure our formulations are cutting edge.  We strive to educate our customers, when they are choosing ingredients for their products, what is the latest and what new studies are finding.

5. Transparency and documentation: Look for manufacturers that provide detailed documentation, including certificates of analysis (COA) for each batch of products, which confirm the quality and purity of the supplements.

Nano9 is all about transparency.  In fact every batch that is created not only give you the certificates of analysis (COA), but we include on it the particle size of the product to ensure that you are getting a nano product. 

6. Compliance with regulatory requirements: Ensure that the manufacturer complies with all relevant regulatory requirements, such as FDA regulations in the United States or equivalent regulations in other countries.

Nano9 always follows this because the consequences of not complying with these regulations is severe.  We don’t want to risk it.  It is always best to follow the guidelines.

7. Reputation and experience: Consider the manufacturer’s reputation and experience in the industry. Look for reviews and testimonials from other companies or individuals who have worked with them.

Nano9 is one of the few nanotechnology companies that provide white labeling for people that are looking to get a product.  We have worked hard to create a good reputation.  We have one of the few nano companies that has a nano bio chemist on staff to help us develop the latest cutting edge products.

8. Customization and flexibility: If you have specific requirements or need customized formulations, choose a manufacturer that offers flexibility and can accommodate your needs.

At nano9 the customer is the priority.  We do all that we can to make sure they are taken care of.  We are one of the few nano companies that does blends.  Making a custom formulation is not a problem at all.  We want to make sure you have what you are envisioning. 

9. Packaging and labeling capabilities: Check if the manufacturer can provide high-quality packaging and labeling services that meet regulatory requirements and enhance the overall presentation of your product.

Remember to thoroughly research and vet potential manufacturers before making a decision. It is also advisable to visit their facilities, if possible, to assess their manufacturing processes and quality control measures first hand.

Michelle LeSueur BeP, CNC, CSN, CNS, CPT

The Remarkable Benefits of Resveratrol

Resveratrol, is a natural compound found in various plants, has gained significant attention in recent years due to its potential health benefits. Resveratrol is an antioxidant-like compound found in red wine, berries, and peanuts. Resveratrol has many benefits from antioxidant and anti-inflammatory properties to neuroprotective effects. Resveratrol also has been known to have antibacterial and antifungal properties as well. Resveratrol has been shown to have a positive impact on human health and well-being. From cardiovascular health to anti-aging properties, resveratrol has emerged as a promising supplement.

Cardiovascular Health:

Resveratrol has been extensively studied for its potential to promote cardiovascular health. Its antioxidant properties help combat oxidative stress, reducing the risk of heart diseases. By improving blood flow and reducing inflammation, resveratrol supports healthy blood vessels and lowers blood pressure. Incorporating resveratrol into your routine may contribute to a healthier heart and overall cardiovascular well-being. Numerous studies have explored resveratrol’s role in preventing and managing cardiovascular (heart-related) disease. Resveratrol exhibits protective effects against blood vessel damage.

Many researchers have concluded that resveratrol is a valuable micronutrient that can prevent heart disease in those at risk and help treat people with progressing cardiovascular conditions.A 2015 review concluded that high doses may help reduce the pressure exerted on artery walls when the heart beats (https://pubmed.ncbi.nlm.nih.gov/24731650/)

Not only is this great as helping the heart, this potent antioxidant and anti-inflammatory compound, also shows promise in protecting brain cells from damage.

Anti-Aging Properties:

Resveratrol has gained popularity for its anti-aging effects. It activates certain genes associated with longevity, promoting cellular health and reducing the signs of aging. By neutralizing free radicals and protecting against oxidative damage, resveratrol helps maintain youthful skin, reducing the appearance of wrinkles and fine lines. Its ability to enhance collagen production also contributes to a more youthful complexion. It also has antioxidant properties which help with aging.   In order to protect the body from free radical cellular damage, polyphenols like resveratrol are important. The anti-inflammatory properties of resveratrol are effective in controlling inflammation throughout the body

Brain Health and Cognitive Function:

Studies suggest that resveratrol may have a positive impact on brain health and cognitive function. It has been found to protect brain cells from damage, potentially reducing the risk of neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Resveratrol’s anti-inflammatory properties and ability to enhance blood flow to the brain may also support improved memory and overall cognitive performance.

Weight Management:

Resveratrol has shown promise in supporting weight management efforts. It activates certain genes that regulate metabolism, potentially aiding in weight loss. Additionally, resveratrol has been found to reduce fat storage and improve insulin sensitivity, which may help prevent obesity and related health issues. Incorporating resveratrol into a balanced diet and exercise routine may assist in achieving and maintaining a healthy weight.

Anti-Cancer Potential:

Research suggests that resveratrol possesses anti-cancer properties. It has been found to inhibit the growth of cancer cells and induce apoptosis (cell death) in various types of cancer, including breast, prostate, and colon cancer. While more studies are needed to fully understand its potential, resveratrol’s ability to combat inflammation and oxidative stress makes it a promising compound in the fight against cancer.

Unfortunately, Resveratrol faces a significant challenge when it comes to absorption in the body due to its large molecular structure. Resveratrol molecules are relatively large, which poses a challenge for their absorption in the body. When consumed orally, these large molecules face barriers in the gastrointestinal tract, making it difficult for them to be efficiently absorbed into the bloodstream. As a result, the bioavailability of resveratrol, or the amount that actually reaches the target tissues, is relatively low.

Another factor that hinders resveratrol absorption is its poor solubility in water. Since our bodies are primarily composed of water, substances that are not water-soluble face challenges in being effectively absorbed. Resveratrol’s hydrophobic nature limits its ability to dissolve in water, further reducing its bioavailability.

Strategies to Enhance Absorption:

To overcome the challenges associated with resveratrol absorption, researchers have explored various strategies. One approach involves formulating resveratrol into nano-sized particles or encapsulating it within liposomes, which can improve its solubility and bioavailability.  Through innovative delivery systems and formulation techniques, we are able to overcome these obstacles and enhance resveratrol absorption. By improving the bioavailability of resveratrol, we can unlock its full potential and harness its remarkable health benefits.

Resveratrol, with its numerous health benefits, has emerged as a highly sought-after supplement in the health and wellness industry. From promoting cardiovascular health and supporting weight management to its potential anti-aging and anti-cancer properties, resveratrol offers a wide range of advantages. By incorporating resveratrol into your daily routine, you can potentially enhance your overall well-being and enjoy the remarkable benefits this natural compound has to offer.

Michelle LeSueur BeP, CNC, CS

What Is Nad & Why Is It All the Rage?

NAD (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells. NAD+ is critical for maintaining the health of our cells, tissues, and bodies. As we age, the problem is we see a gradual change and drop in this important coenzyme.  NAD decline is linked to many age related diseases.  It plays a crucial role in various biological processes, including:

Energy production: NAD is involved in cellular respiration, the process by which cells convert nutrients into energy. It acts as a coenzyme in the electron transport chain, facilitating the transfer of electrons (a series of reactions that occur in the mitochondria of cells) and the production of ATP (adenosine triphosphate), the primary energy currency of cells. During cellular respiration, nutrients, including carbohydrates, fats, and proteins, are broken down to produce ATP (adenosine triphosphate), the primary energy source for cellular activities. NAD acts as an electron carrier, accepting and donating electrons during these reactions, which are essential for ATP synthesis.

DNA repair: NAD is required for the activity of certain enzymes involved in DNA repair mechanisms. It helps repair damaged DNA and maintain genomic stability.

Cellular signaling: NAD is involved in various signaling pathways within cells. It serves as a substrate for enzymes called sirtuins, which regulate gene expression, cellular metabolism, and stress responses. NAD also participates in redox reactions.  Redox reactions are when there is  the transfer of electrons between molecules. These reactions are crucial for the breakdown of nutrients and the production of energy. NAD accepts electrons from molecules being oxidized (losing electrons) and donates them to molecules being reduced (gaining electrons), allowing for the efficient extraction of energy from nutrients.

Aging and longevity: NAD levels decline with age, and this decline has been associated with various age-related diseases and conditions. Boosting NAD levels through supplementation or activation of NAD-producing enzymes like sirtuins has been suggested to have potential anti-aging effects.

Some say that NAD helps detox the body.  The body has other mechanisms in place to prevent or minimize the entry of pollutants and toxins into the bloodstream. While NAD does not directly prevent the entry of pollutants and toxins into the bloodstream, it is involved in maintaining overall cellular health and function, which indirectly supports the body’s ability to handle and eliminate harmful substances.

Effects on Mood:

NAD (nicotinamide adenine dinucleotide) has been implicated in mood regulation, although the exact mechanisms are still being studied. Here are a few ways in which NAD may affect mood:

Energy production: NAD is involved in cellular respiration and the production of ATP, the energy currency of cells. Adequate energy levels are essential for optimal brain function and neurotransmitter synthesis, which can influence mood. NAD’s role in energy production may indirectly impact mood regulation.

Neurotransmitter synthesis: NAD is required for the synthesis of certain neurotransmitters, including serotonin, dopamine, and norepinephrine. These neurotransmitters play crucial roles in regulating mood, emotions, and overall mental well-being. NAD’s involvement in neurotransmitter synthesis suggests it may have an impact on mood regulation.

Oxidative stress and inflammation: NAD is involved in redox reactions and acts as an antioxidant, helping to neutralize harmful free radicals and reduce oxidative stress. High levels of oxidative stress and inflammation have been associated with mood disorders such as depression and anxiety. By reducing oxidative stress and inflammation, NAD may have a positive impact on mood.

Sirtuin activation: NAD is a coenzyme for sirtuins, a group of enzymes involved in various cellular processes, including stress response and gene expression. Sirtuins have been linked to mood regulation, and NAD’s role in sirtuin activation may contribute to its effects on mood.

It’s important to note that while NAD may have potential effects on mood regulation, more research is needed to fully understand its mechanisms and therapeutic implications. Additionally, individual responses to NAD and its impact on mood can vary, and it should not be considered a standalone treatment for mood disorders.

How does NAD assist and improve Metabolism, and fat digestion?

NAD (nicotinamide adenine dinucleotide) plays a role in metabolism and fat digestion through its involvement in cellular respiration and energy production.  NAD is involved in the breakdown of fats, a process called lipolysis. When the body requires energy, stored fats are broken down into fatty acids and glycerol. NAD participates in the oxidation of fatty acids, facilitating their conversion into acetyl-CoA, a molecule that enters the citric acid cycle (also known as the Krebs cycle) to generate ATP.

By participating in cellular respiration, fat metabolism, and redox reactions, NAD helps improve metabolism and fat digestion. It ensures the efficient breakdown of nutrients, including fats, and the production of ATP, which is necessary for various metabolic processes in the body. However, it’s important to note that NAD’s role is as a coenzyme, and its effects on metabolism and fat digestion are indirect, supporting the enzymatic reactions involved in these processes.

Overall, NAD plays a vital role in cellular metabolism, energy production, DNA repair, and cellular signaling, making it essential for various physiological processes in the body.

Michelle LeSueur BeP, CNC, CSN, CNS, CPT

Vitamin D and Appetite Control

We need sunshine, not just for our mood, but for many things that happen in our bodies. When you understand how important vitamin D is to your health and the role it plays in your life, you appreciate the sun even more.

Vitamin D is a group of fat-soluble prohormones and many people don’t realize this. Its major function is to promote the absorption of calcium and phosphorus from the food we eat in our intestinal tract.  It also helps with the re-absorption of calcium in the kidneys.

The best way to get your vitamin D is to spend 15 minutes a day in the sun.  Early morning or late afternoon is the best.   Unfortunately, most people do not have the time and depending where they live it can be too hot or cold.  

Research shows the importance of vitamin D and the protection from cancer.  The vitamin D hormone has been found to induce death of cancer cells in vitro and in vivo. Research also shows that by raising the amount of vitamin D in the blood appears to help some people — at least those deficient in the vitamin — reduce their risk of heart disease by about 30%.  The findings, though preliminary, support further investigation of the interplay between vitamin D and heart health. It is important to note that dark- skinned individuals and the elderly also produce less vitamin D, and many folks don’t get enough of the nutrient from dietary sources like fatty fish.

It is amazing when people check their vitamin D levels they find that they are very low.   Even in Southern California where you would think they get plenty of sun, people have vitamin D deficiencies, because so many people use sunscreen.  But those who live at northern latitudes, follow a strict vegetarian diet, have a milk allergy, suffer from obesity or have a darker skin pigment are usually at a higher risk of having a vitamin D deficiency. Infants who are solely breastfed have also been found to have a deficiency because breast milk contains a small amount of vitamin D.

So how do you know you have a deficiency?  In most cases, a vitamin D deficiency is not easy to recognize. Muscle weakness, fatigue, muscle spasms and bone pain are common symptoms but in more severe cases, the deficiency can lead to rickets — is a disorder that can cause impaired growth in addition to dental and skeletal deformities. Your family physician can do a simple blood test if you are worried that you or your family might be at risk. Also there is a coloration between breast cancer and vitamin D deficiencies.  A good friend of mine who is a M.D. works with a lot of breast cancer patients.

A 2006 study by researchers at the University of California at San Diego, involving more than 120,000 women, showed that those women with the highest blood levels of vitamin D had a 50 percent reduced risk of breast cancer. Their study was published in the journal Nutrition Reviews.

Vitamin D is very important when it comes to your appetite. If you find you are hungry all the time, check your vitamin D. People with low Vitamin D tend to be hungry all the time. If this sounds like you get your levels checked.

Vitamin D deficiency can occur for a number of reasons:

You don’t consume the recommended levels of the vitamin over time. This is likely if you follow a strict vegetarian diet, because most of the natural sources are animal- based, including fish and fish oils, egg yolks, cheese, and beef liver.

Your exposure to sunlight is limited. Because the body makes vitamin D when your skin is exposed to sunlight, you may be at risk of deficiency if you are homebound, live in northern latitudes, wear long robes or head coverings for religious reasons, or have an occupation that prevents sun exposure.

You have dark skin. The pigment melanin reduces the skin’s ability to make vitamin D in response to sunlight exposure. Some studies show that older adults with darker skin are at high risk of vitamin D deficiency.

Your kidneys cannot convert vitamin D to its active form. As people age their kidneys are less able to convert vitamin D to its active form, thus increasing their risk of vitamin D deficiency.  (I would note that bodybuilders who do tons of protein and do not use enzymes to metabolize and break protein down. I will see this at a younger age.)

Your digestive tract cannot adequately absorb vitamin D. Certain medical problems, includingCrohn’s disease, cystic fibrosis, and celiac disease, can affect your intestine’s ability to absorb vitamin D from the food you eat.

You are obese. Vitamin D is extracted from the blood by fat cells, altering its release into the circulation. People with a body mass index of 30 or greater often have low blood levels of vitamin D.

You can find Vitamin D in many places, but not all Vitamin D is the same. It is important to find a source that your body can use and has a delivery system that bypasses digestion or enhances the ioavailability in some way. Nano is the best I have found. I had a person that had low vitamin D.  My normal protocol was 20K IU’s for 3 months of a good D3K2 and then  Follow up with testing a few months later to see where your numbers are coming in. Then I moved to a nano form and did only 4K IU with K2 and got to the higher levels in 2 months.

Testing in 2-3 months to make sure you are between 90-100 is where you want to be.  Then you can cut back. 

Michelle LeSueur BeP, CNC, CSN, CNS, CPT